Cystatin C for the assessment of GFR in neonates with congenital renal anomalies.
نویسندگان
چکیده
Department of Paediatrics, Children’s Hospital, London Health Science Centre, University of Western Ontario, London, Ontario, Canada, Department of Pathology and Laboratory Medicine, DSB 4044, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada, Department of Medicine, University of Western Ontario, London, Ontario, Canada and Department of Paediatrics, University of Ottawa, Ottawa, Ontario, Canada
منابع مشابه
Comparative Assessment of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Cystatin C as Early Biomarkers for Early Detection of Renal Failure in Patients with Hypertension
Background: Hypertension is one the most common causes of chronic kidney disease (CKD). One of the major concerns in hypertensive patients is early detection of renal disorders. In the past, serum creatinine (Scr) concentration was used as a marker of kidney function, but it proffers a late reflection of reduced glomerular filtration rate. Cystatin C and neutrophil gelatinase-associated lipocal...
متن کاملبررسی مقایسهای ارزش تشخیصی سیستاتین C و کراتینین سرمی در ارزیابی عملکرد کلیه پیوندی در بیماران گیرنده کلیه در دوران اولیه پس از پیوند
Background &Aim: Early detection of decreasing glomerular filtration rate (GFR) is critical to prevent graft rejection in post-transplantation period. Serum creatinine has several drawbacks as a marker of GFR, so serum cystatin C has been proposed as an alternative GFR marker. Thus, we prospectively evaluated the diagnostic value of cystatin C measurements compared with serum creatinine in t...
متن کاملSERUM CYSTATIN C AS A NEW MARKER OF GLOMERULAR FILTRATION RATE (GFR)
Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. The cystatin C gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin C by most cells. This protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. Because of the...
متن کاملبررسی ارتباط میزان فیلتراسیون گلومرولی (GFR) با عملکرد کبد در بیماران سیروز کبدی
Background and purpose: Serum creatinine and its derived formulae in estimating glomerular filtration rate is not accurate in cirrhotic patients because of decreased muscle mass and secretion and excretion functional impairment of liver. This study aimed at investigating the accuracy of serum cystatin C in determining GFR and examining the relationship between synthetic and excretory liver func...
متن کاملSymmetrical dimethylarginine outperforms CKD-EPI and MDRD-derived eGFR for the assessment of renal function in patients with adult congenital heart disease.
BACKGROUND/AIMS Adults with congenital heart disease exhibit a 3-fold higher mortality in the presence of chronic kidney disease, hence assessment of renal function is crucial in this patient population. Formulas for the estimation of glomerular filtration rate (GFR) have not been evaluated in this patient population. Therefore, this study compares different markers and equations for the estima...
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ورودعنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 27 9 شماره
صفحات -
تاریخ انتشار 2012